How to get from Santiago to Arequipa by car, truck, walk, bike

Distance between Santiago and Arequipa is 2360 kilometers (1463 miles).
Driving distance from Santiago to Arequipa is 3438 kilometers (2132 miles)

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Route Map

4 Ways from Santiago (Chile/Region Metropolitana) to Arequipa (Peru/Cusco)

Choose 1 of the options below and start your journey

Route instructions

1. Continue onto Plaza de Armas 845 m
2. Turn right onto Avenida Manuel Rodríguez Norte 150 m
3. Keep left onto Acceso Autopista Central 24.25 km
4. Keep left onto Ruta 5 Norte, 5 433.11 km
5. Keep right 672 m
6. Keep right onto Domeyko 381 m
7. Continue onto Miraflores 184 m
8. Keep right onto Miraflores 501.45 km
9. Keep right 979 m
10. Keep right onto Costanera 190 m
11. At roundabout, take exit 3 221 m
12. Turn right onto Ruta 5 Norte, 5 486.79 km
13. Continue onto Ruta 5 Norte, 5 503.58 km
14. Keep right 3.14 km
15. Keep left 661 m
16. Turn slight right onto Ruta 5 Norte, 5 105.48 km
17. At roundabout, take exit 1 onto Avenida Capitán Ávalos, 5 390 m
18. At roundabout, take exit 2 onto Avenida Capitán Ávalos, 5 2.20 km
19. Turn left onto Avenida Renato Roca 1.86 km
20. Turn right onto Santiago Arata Gandolfo 639 m
21. Continue onto Santiago Arata Gandolfo 3.19 km
22. At roundabout, take exit 2 onto Ruta 5 Norte 3.37 km
23. At roundabout, take exit 2 onto Ruta 5 Norte, 5 10.52 km
24. Turn left onto Carretera Escritos - Santa Rosa - Conchal, TA-645 15.54 km
25. Continue onto TA-643 16.69 km
26. Continue onto TA-643 893 m
27. Continue onto PE-1SD 103.65 km
28. Keep left 7.33 km
29. Turn right onto José Joaquín Inclán 338 m
30. Turn left onto Avenida 28 de Julio 400 m
31. Turn right onto Moquegua 266 m
32. Turn left 191 m
33. Continue onto Avenida Costero Miramar 1.79 km
34. Keep right onto PE-1SD 1.57 km
35. Turn slight right onto Carretera Costanera Norte Ilo - La Punta, PE-1SD 91.82 km
36. Keep left 4.65 km
37. At roundabout, take exit 1 436 m
38. Turn left onto 15 A, PE-1SD 9.21 km
39. At roundabout, take exit 1 onto 15 A, PE-1SD 2.27 km
40. Turn slight right onto Avenida Tambo, PE-1SD 10.64 km
41. At roundabout, take exit 1 onto PE-1SD 6.87 km
42. At roundabout, take exit 1 onto PE-1SD 8.07 km
43. At roundabout, take exit 2 onto Carretera Costanera Sur, PE-1SD 89.00 km
44. At roundabout, take exit 2 onto Panamericana Sur, PE-1S 12.00 km
45. Turn left 85 m
46. Turn right onto Avenida Lima 349.78 km
47. Continue onto Panamericana Sur, PE-1S 38.41 km
48. Keep right onto Calle Huayna Cápac 291 m
49. Turn slight right onto PE-30A 83.49 km
50. Keep left onto Via Hualla-Nazca, AY-670 93.37 km
51. Turn left onto AY-114 28.81 km
52. Turn right onto AY-114 3.88 km
53. Turn left 189 m
54. Turn left onto AY-114 9.62 km
55. Turn right onto PE-30D 285 m
56. Turn right onto PE-30D 62.25 km
57. Turn sharp left 999 m
58. Turn left onto PE-30D 3.80 km
59. Turn sharp left 77 m
60. Turn right 1.15 km
61. Turn sharp left onto PE-30D 2.73 km
62. Continue onto Avenida Los Morochucos 659 m
63. Turn slight left onto Avenida 24 de Junio, PE-30D 3.27 km
64. Continue onto PE-32A 28.24 km
65. Turn left onto PE-3S 22.63 km
66. Turn left 859 m
67. Turn right 136 m
68. Turn left onto PE-3S 7.90 km
69. Turn left 187 m
70. Turn right onto Carretera Ayacucho-Cusco, PE-3S 21 m
71. Turn left 386 m
72. Turn left onto Jirón Los Algarobos 13 m
73. Turn sharp right onto Carretera Ayacucho-Cusco, PE-3S 149 m
74. Turn left onto Avenida Nicaragua 741 m
75. Turn sharp right onto Avenida Venezuela 135 m
76. Turn left onto Avenida 9 de Diciembre 468 m
77. Continue onto Avenida 9 de Diciembre, PE-3SL 804 m
78. Turn left 741 m
79. Continue 23 m
80. Turn right 3.89 km
81. Turn right onto Longitudinal de la Sierra Sur, PE-3S 80 m
82. Turn left 709 m
83. Turn left onto Longitudinal de la Sierra Sur, PE-3S 2.31 km
84. Turn sharp right 7.80 km
85. Keep left 2.98 km
86. Continue onto PE-28B 2.71 km
87. Turn right 205 m
88. Turn left 393 m
89. Continue onto Jirón San Martín 310 m
90. Turn slight left onto Jirón Cordova 9 m
91. Turn right onto PE-28B 3.85 km
92. Keep left 361 m
93. Turn slight left onto PE-28B 35.98 km
94. Turn right 144 m
95. Turn right onto PE-28B 12 m
96. Turn left 101 m
97. Turn sharp left 18 m
98. Turn right 73 m
99. Turn left onto PE-28B 88 m
100. Turn right 171 m
101. Turn left 6 m
102. Turn right 54 m
103. Turn right 62 m
104. Turn left 548 m
105. Turn sharp left 243 m
106. Turn slight right onto PE-28B 15.95 km
107. Turn right onto PE-28B 31.38 km
108. Turn right onto PE-28B 46.75 km
109. Turn left 3.23 km
110. Turn sharp left onto PE-28H 14.98 km
111. Turn right onto PE-28H 30.26 km
112. Turn slight left 109 m
113. Turn left 8.05 km
114. Keep left 5.33 km
115. Turn right 93 m
116. Turn left 40 m
117. Keep right 1.63 km
118. Turn sharp right 442 m
119. Keep right 2.37 km
120. Keep right 314 m
121. Arrive at destination 0 m
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Questions and Answers

What is the cheapest way to get from Santiago (Chile/Region Metropolitana) to Arequipa (Peru/Cusco)?
How do I get from Santiago (Chile/Region Metropolitana) to Arequipa (Peru/Cusco) the fastest?
How long does it take to get from Santiago (Chile/Region Metropolitana) to Arequipa (Peru/Cusco)?