How to get from Greenville to Knoxville by car, truck, walk, bike
Distance between Greenville and Knoxville is 185 kilometers (115 miles).
Driving distance from Greenville to Knoxville is 270 kilometers (167 miles)
Route Map
Routes from greenville-south-carolina to knoxville-tennessee
4 Ways from Greenville (United States/South Carolina) to Knoxville (United States/Tennessee)
Choose 1 of the options below and start your journey
Cheapest
Fastest
Route instructions
1. Continue onto East Coffee Street 17 m
2. Turn right onto North Main Street 286 m
3. Turn left onto College Street 918 m
4. Turn right onto Rutherford Street 395 m
5. Turn slight right onto Rutherford Street, US 276 10.23 km
See more
Questions and Answers
What is the cheapest way to get from Greenville (United States/South Carolina) to Knoxville (United States/Tennessee)?
How do I get from Greenville (United States/South Carolina) to Knoxville (United States/Tennessee) the fastest?
How long does it take to get from Greenville (United States/South Carolina) to Knoxville (United States/Tennessee)?
Trips from Greenville
GreenvilleQuincyGreenvilleJohnson CityGreenvilleSalt Lake CityGreenvilleWestonGreenvilleFresnoGreenvilleWinston-SalemGreenvilleManhattanGreenvilleLexingtonGreenvilleFargoTrips to Knoxville (United States/Tennessee)
ElyriaKnoxvilleGainesvilleKnoxvilleRutlandKnoxvilleLawrenceKnoxvilleTracyKnoxvilleBolivarKnoxvilleSalt Lake CityKnoxvilleWellsKnoxvilleButlerKnoxvilleOther interesting routes
AlabamaGeorgiaNorth CarolinaSouth CarolinaTennesseeAlabamaGeorgiaSouth CarolinaInformation about Stations
All station in Greenville (United States/South Carolina)
Greenville Greenville StationGreenville Greenville Station All station in Knoxville (United States/Tennessee)
Three Rivers Rambler KnoxvilleJackson Terminal Knoxville Station