How to get from Charleston to Cape Girardeau by car, truck, walk, bike

Distance between Charleston and Cape Girardeau is 1006 kilometers (624 miles).
Driving distance from Charleston to Cape Girardeau is 1209 kilometers (750 miles)

CharlestonCape Girardeau
Leaving from
Going to

Route Map

Routes from charleston-south-carolina to cape-girardeau-missouri

4 Ways from Charleston (United States/South Carolina) to Cape Girardeau (United States/Missouri)

Choose 1 of the options below and start your journey

Route instructions

1. Continue onto Warren Street 58 m
2. Turn right onto Coming Street 933 m
3. Keep right 932 m
4. Keep left onto Septima Clark Expressway, I 26 418.23 km
5. Keep left onto US 74, US 64 Truck 168.64 km
6. Keep left onto I 40 40.08 km
7. Keep right onto I 40 245.86 km
8. Keep right 18.68 km
9. Keep right 178.96 km
10. Keep right onto I 24 29.46 km
11. Keep right 414 m
12. Keep left 799 m
13. Keep left 64 m
14. Turn left onto Alben Barkley Drive, US 62 13.83 km
15. Keep right onto KY 286 26.74 km
16. Turn slight right onto Court Street, KY 121 528 m
17. Turn right onto 4th Street, US 51, US 62 436 m
18. Turn left onto Green Street, US 51, US 60, US 62 7.73 km
19. Keep right onto US 51 1.35 km
20. Turn slight right onto Washington Avenue, US 51 19.11 km
21. Turn left onto Illinois Route 3, IL 3 28.24 km
22. Turn left 6.60 km
23. Keep right 306 m
24. At roundabout, take exit 1 onto Morgan Oak Street, MO 177 239 m
25. Turn left onto South Spanish Street, MO 177 667 m
26. Turn left onto Independence Street 267 m
27. Turn left onto South Fountain Street 39 m
28. Arrive at destination 0 m
See more

Questions and Answers

What is the cheapest way to get from Charleston (United States/South Carolina) to Cape Girardeau (United States/Missouri)?
How do I get from Charleston (United States/South Carolina) to Cape Girardeau (United States/Missouri) the fastest?
How long does it take to get from Charleston (United States/South Carolina) to Cape Girardeau (United States/Missouri)?